A rationally designed macrocyclic cavitand that kills bacteria with high efficacy and good selectivity
Literature Information
Jinny Choi, Jeeyeon Kim, Kimoon Kim, Sung-Tae Yang, Jae-Il Kim, Sangyong Jon
An amphiphilic macrocyclic cavitand that shows good antibacterial activity, comparable to that of peptide-based antibiotics was developed by rational design and its antibacterial selectivity over mammalian cells was examined.
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![2-Hydroxy-4-[({[(4-methylphenyl)sulfonyl]oxy}acetyl)amino]benzoic acid structure 2-Hydroxy-4-[({[(4-methylphenyl)sulfonyl]oxy}acetyl)amino]benzoic acid structure](https://static.chemtradehub.com/structs/501/501919-59-1-579f.webp)