Effect of peracetylation on the conformation of γ-cyclodextrin

Literature Information

Publication Date 2007-01-10
DOI 10.1039/B616681D
Impact Factor 6.222
Authors

Mino R. Caira, Giampiero Bettinetti, Milena Sorrenti, Laura Catenacci, Dyanne Cruickshank, Kate Davies


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Abstract

The well-known, fourfold symmetry of the γ-CD molecule in its solid inclusion complexes is lost on peracetylation, which yields a highly distorted host molecule in which self-inclusion of acetyl residues divides the macrocyclic cavity into two distinct sub-cavities that accommodate solvent molecules.

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