Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein

Literature Information

Publication Date 2006-09-05
DOI 10.1039/B610461D
Impact Factor 6.222
Authors

Manfred T. Reetz, Jérôme J.-P. Peyralans, Andrea Maichele, Yu Fu, Matthias Maywald


View Original

Abstract

The concept of utilizing the methods of directed evolution for tuning the enantioselectivity of synthetic achiral metal–ligand centers anchored to proteins has been implemented experimentally for the first time.

Related Literature

Mesocellular polymer foams with unprecedented uniform large mesopores and high surface areas

Jinwoo Lee, Jaeyun Kim, Sang-Wook Kim, Chae-Ho Shin, Taeghwan Hyeon

2004-02-06 Communication

DOI: 10.1039/B310713B

A novel azulene synthesis from the Ramirez ylide involving two different modes of its reaction with activated alkynes

Lee J. Higham, P. Gabriel Kelly, David M. Corr, Helge Müller-Bunz, Brian J. Walker, Declan G. Gilheany

2004-02-11 Communication

DOI: 10.1039/B316759C

Living cationic polymerisation of styrene in an ionic liquid

R. Vijayaraghavan, D. R. MacFarlane

2004-02-13 Communication

DOI: 10.1039/B315100J

Hydrogen adsorption in the nanoporous metal-benzenedicarboxylate M(OH)(O2C–C6H4–CO2) (M = Al3+, Cr3+), MIL-53

Gérard Férey, Michel Latroche, Christian Serre, Franck Millange, Thierry Loiseau, Annick Percheron-Guégan

2003-11-04 Communication

DOI: 10.1039/B308903G

Terminally functionalized polyisobutylene oligomers as soluble supports in catalysis

David E. Bergbreiter, Jun Li

2003-11-27 Communication

DOI: 10.1039/B312368E

A concise stereocontrolled formal total synthesis of (±)-podophyllotoxin using sulfoxide chemistry

Mike Casey, Claire M. Keaveney

2003-12-05 Communication

DOI: 10.1039/B312245J

Preparation of highly accessible mordenite coatings on ceramic monoliths at loadings exceeding 50% by weight

M. A. Ulla, E. Miro, R. Mallada, J. Coronas, J. Santamaría

2004-01-29 Communication

DOI: 10.1039/B315386J

Multiple active oxidants in competitive epoxidations catalyzed by porphyrins and corroles

James P. Collman, Li Zeng, Richard A. Decréau

2003-11-03 Communication

DOI: 10.1039/B310763A

Helical supramolecular host with aquapores anchoring alternate molecules of helical water chains‡

Arindam Mukherjee, Manas K. Saha, Munirathinam Nethaji, Akhil R. Chakravarty

2004-02-12 Communication

DOI: 10.1039/B316275C

You might also like

Compound Q&A

How should waste containing 2-Ethyl-4-Methyl-1H-Imidazole-5-Carbaldehyde (CAS: 88634-80-4) be handled?

Waste containing 2-Ethyl-4-Methyl-1H-Imidazole-5-Carbaldehyde (CAS: 88634-80-4) ...

88634-80-42-Ethyl-4-Methyl-1H-...
Compound Q&A

What industries use Triethoxy(octyl)silane (CAS: 1385031-14-0)?

Triethoxy(octyl)silane (CAS: 1385031-14-0) is widely used in the pharmaceuticals...

1385031-14-0Triethoxy(octyl)sila...
Compound Q&A

Are there alternatives to 3-iodo-7-nitro-1H-indazole (CAS: 864724-64-1) in synthesis?

Several alternatives to 3-iodo-7-nitro-1H-indazole (CAS: 864724-64-1) exist in t...

864724-64-13-iodo-7-nitro-1H-in...
Compound Q&A

Are there alternatives to Benzene, bis[(trimethoxysilyl)ethyl] (CAS: 266317-71-9) in synthesis?

Yes, there are alternatives to Benzene, bis[(trimethoxysilyl)ethyl] (CAS: 266317...

266317-71-9Benzene, bis[(trimet...
Compound Q&A

Is Isothiazole-3-carbonitrile (CAS: 1452-17-1) safe?

Isothiazole-3-carbonitrile (CAS: 1452-17-1) is generally considered safe when us...

1452-17-1Isothiazole-3-carbon...
Compound Q&A

Is (3-Chlorophenyl)methanol (CAS: 873-63-2) safe?

(3-Chlorophenyl)methanol (CAS: 873-63-2) is considered low to moderately toxic. ...

873-63-2(3-Chlorophenyl)meth...
Compound Q&A

How is (2S,3S)-2-Hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-(2-naphthyl)propanoic acid (CAS: 959583-98-3) typically synthesized?

(2S,3S)-2-Hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-(2-naphthyl)pr...

959583-98-3(2S,3S)-2-Hydroxy-3-...
Compound Q&A

What precautions should be taken when handling Methyl 2-(bromomethyl)-5-methoxybenzoate (CAS: 788081-99-2)?

Proper handling of methyl 2-(bromomethyl)-5-methoxybenzoate requires the use of ...

788081-99-2Methyl 2-(bromomethy...
Compound Q&A

What is 6,8-Dibromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 904805-36-3)?

6,8-Dibromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS: 904805-36-3) is an aro...

904805-36-36,8-Dibromoimidazo[1...
Compound Q&A

Is 3-Amino-5-bromo-2-pyridinecarbonitrile (CAS: 573675-27-1) safe?

3-Amino-5-bromo-2-pyridinecarbonitrile is considered safe when handled under pro...

573675-27-13-Amino-5-bromo-2-py...

Source Journal

Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
Articles per Year: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.