PNA forms an i-motif

Literature Information

Publication Date 2005-09-23
DOI 10.1039/B510405J
Impact Factor 6.222
Authors

Yamuna Krishnan-Ghosh, Elaine Stephens, Shankar Balasubramanian


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Abstract

A C-rich PNA hexanucleotide, p(C5T), has been shown to form an i-motif by nanoelectrospray ionization mass spectrometry coupled with H/D exchange, to have thermal stability comparable with its DNA analogue, but to exist over a much narrower pH range.

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