Structure elucidation of a novel family of mycolactonetoxins from the frog pathogen Mycobacterium sp. MU128FXT by mass spectrometry

Literature Information

Publication Date 2005-08-05
DOI 10.1039/B506835E
Impact Factor 6.222
Authors

Hui Hong, Tim Stinear, Paul Skelton, Jonathan B. Spencer, Peter F. Leadlay


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Abstract

Structures are proposed, based on LC-ion trap MSn analysis and high-resolution FTICR MS/MS analysis, for a novel family of mycolactone toxins isolated from the frog pathogen MU128FXT and differing from those produced by the human pathogen M. ulcerans MUAgy99 in having an altered polyketide side chain.

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