Radical-carbanion cyclo-coupling in armed aromatics: overriding steric hindrance to ring closure

Literature Information

Publication Date 2005-08-04
DOI 10.1039/B506391D
Impact Factor 6.222
Authors

Mark D. Roydhouse, John C. Walton


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Abstract

ω-(2-Halophenyl)alkyl-2-oxazolines were prepared and reacted via base promoted intramolecular coupling of radical with carbanionic centres to yield 1-phenyl-1-oxazolino-indan and -tetralin derivatives containing quaternary C-atoms.

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