Intermolecular rhodium-catalyzed [2 + 2 + 2] carbocyclization reactions of 1,6-enynes with symmetrical and unsymmetrical alkynes

Literature Information

Publication Date 2005-07-07
DOI 10.1039/B505383H
Impact Factor 6.222
Authors

P. Andrew Evans, James R. Sawyer, Kwong Wah Lai, John C. Huffman


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Abstract

The crossed intermolecular rhodium-catalyzed [2 + 2 + 2] carbocyclization of carbon and heteroatom tethered 1,6-enynes can be accomplished with symmetrical and unsymmetrical alkynes, to afford the corresponding bicyclohexadienes in an efficient and highly selective manner.

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DOI: 10.1039/C5QO90050F

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DOI: 10.1039/C6QO90001A

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