First osmium-catalysed ketamination of alkenes

Literature Information

Publication Date 2005-06-01
DOI 10.1039/B505278P
Impact Factor 6.222
Authors

Amparo Villar, Claas H. Hövelmann, Martin Nieger, Kilian Muñiz


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Abstract

Conditions for a first oxidative conversion of alkenes into 2-amino ketones are described, which yield racemic products within a direct oxidation pathway and 2-amino ketones with up to 99% enantiomeric excess from the corresponding enantiopure amino alcohols.

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