Asymmetric Carroll rearrangement of allyl α-acetamido-β-ketocarboxylates catalysed by a chiral palladium complex

Literature Information

Publication Date 2005-07-07
DOI 10.1039/B505105C
Impact Factor 6.222
Authors

Ryoichi Kuwano, Naoki Ishida, Masahiro Murakami


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Abstract

Asymmetric decarboxylative rearrangement (Carroll rearrangement) of allyl α-acetamido-β-ketocarboxylates was catalysed by a palladium complex modified with a chiral phosphine ligand, giving optically active γ,δ-unsaturated α-aminoketones with up to 90% ee.

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