Analysis of key steps in the catalytic cross-coupling of alkyl electrophiles under Negishi-like conditions
Literature Information
Gavin D. Jones, Chris McFarland, Thomas J. Anderson, David A. Vicic
The use of tpy′ (tpy′ = 4,4′,4″-tri-tert-butyl-terpyridine) as a ligand for nickel allows for the isolation of a Ni(I)–alkyl complex and a Ni(II)–alkyl halide complex, both of which can be used as mechanistic probes of key steps in alkyl cross-coupling reactions.
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![4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione structure 4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione structure](https://static.chemtradehub.com/structs/209/2093416-31-8-3162.webp)



