Superparamagnetic gadonanotubes are high-performance MRI contrast agents
Literature Information
Balaji Sitharaman, Kyle R. Kissell, Keith B. Hartman, Lesa A. Tran, Andrei Baikalov, Irene Rusakova, Yanyi Sun, Htet A. Khant, Steven J. Ludtke, Wah Chiu, Sabrina Laus, Éva Tóth, Lothar Helm, André E. Merbach, Lon J. Wilson
We report the nanoscale loading and confinement of aquated Gd3+n-ion clusters within ultra-short single-walled carbon nanotubes (US-tubes); these Gd3+n@US-tube species are linear superparamagnetic molecular magnets with Magnetic Resonance Imaging (MRI) efficacies 40 to 90 times larger than any Gd3+-based contrast agent (CA) in current clinical use.
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