Novel formation and use of a Nicholas carbocation in the synthesis of highly substituted tetrahydrofurans

Literature Information

Publication Date 2004-09-17
DOI 10.1039/B411367E
Impact Factor 6.222
Authors

Steven D. R. Christie, Ryan J. Davoile, Mark R. J. Elsegood, Ross Fryatt, Raymond C. F. Jones, Gareth J. Pritchard


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Abstract

The first formation of a Nicholas carbocation through cleavage of a carbon–carbon σ bond has allowed the preparation of highly substituted tetrahydrofurans in a formal dipolar cycloaddition reaction.

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