Ruthenium- and gold-catalysed sequential reactions: a straightforward synthesis of substituted oxazoles from propargylic alcohols and amides
Literature Information
Marilyn Daisy Milton, Youichi Inada, Yoshiaki Nishibayashi, Sakae Uemura
A convenient and straightforward one-pot reaction of propargylic alcohols bearing a terminal alkyne moiety with amides by the sequential action of ruthenium and gold catalysts gives the corresponding substituted oxazoles in good yields with a complete regioselectivity.
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