Ruthenium- and gold-catalysed sequential reactions: a straightforward synthesis of substituted oxazoles from propargylic alcohols and amides

Literature Information

Publication Date 2004-10-13
DOI 10.1039/B411180J
Impact Factor 6.222
Authors

Marilyn Daisy Milton, Youichi Inada, Yoshiaki Nishibayashi, Sakae Uemura


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Abstract

A convenient and straightforward one-pot reaction of propargylic alcohols bearing a terminal alkyne moiety with amides by the sequential action of ruthenium and gold catalysts gives the corresponding substituted oxazoles in good yields with a complete regioselectivity.

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