Convenient magnesiation of aromatic and heterocyclic rings bearing a hydroxy group in presence of LiCl
Literature Information
Felix Kopp, Arkady Krasovskiy, Paul Knochel
The reaction of various iodophenols with MeMgCl in presence of LiCl followed by the addition of i-PrMgCl provides the corresponding magnesiated magnesium phenolates as THF soluble reagents; this approach can be extended to heterocyclic compounds bearing a hydroxy group like pyridines and quinolines.
Related Literature
Mobility driven thermoelectric and optical properties of two-dimensional halide-based hybrid perovskites: impact of organic cation rotation
Hardik L. Kagdada, Sanjeev K. Gupta, Dheeraj K. Singh
DOI: 10.1039/D1CP05724C
Structure, hydrogen bond dynamics and phase transition in a model ionic liquid electrolyte
Peter Stange, Alexander G. Stepanov
DOI: 10.1039/D2CP00452F
Zooming in on the initial steps of catalytic NO reduction using metal clusters
Joost M. Bakker, Fumitaka Mafuné
DOI: 10.1039/D1CP05760J
Collision-assisted stripping for determination of microsolvation-dependent protonation sites in hydrated clusters by cryogenic ion trap infrared spectroscopy: the case of benzocaineH+(H2O)n‡
Fuad Haddad
DOI: 10.1039/D1CP05762F
Effects of stearyl alcohol monolayer on the structure, dynamics and vibrational sum frequency generation spectroscopy of interfacial water
Banshi Das, Amalendu Chandra
DOI: 10.1039/D1CP04944E
Cohesive properties of PbBi/Fe3O4 and PbBi/(Fe,Cr)3O4 interfaces
L. Sun, P. Deng, J. Zhao, H. R. Gong, C. P. Liang
DOI: 10.1039/D1CP05953J
Fundamental studies of vibrational resonance phenomena by multivalued resummation of the divergent Rayleigh–Schrödinger perturbation theory series: deciphering polyad structures of three H216O isotopologues
Xuanhao Chang, Egor O. Dobrolyubov, Sergey V. Krasnoshchekov
DOI: 10.1039/D1CP04279C
Ultralow work function of the electride Sr3CrN3
Cuicui Wang, Miaoting Xu, Keith T. Butler, Lee A. Burton
DOI: 10.1039/D1CP05623A
Thermal tuning of terahertz metamaterial absorber properties based on VO2
Zhipeng Zheng, Yao Luo, Hua Yang, Zao Yi, Jianguo Zhang, Qianjv Song, Wenxing Yang, Chao Liu, Xianwen Wu, Pinghui Wu
DOI: 10.1039/D2CP01070D
You might also like
What precautions should be taken when handling lithium chloride hydrate (1:1:1) (CAS: 16712-20-2)?
When handling lithium chloride hydrate (1:1:1) (CAS: 16712-20-2), it is importan...
Is 4-(4H-1,2,4-Triazol-4-yl)piperidine (CAS: 690261-92-8) safe?
4-(4H-1,2,4-Triazol-4-yl)piperidine is generally considered safe for use in phar...
How should waste containing 1,3-Thiazole-2-carboxamide (CAS: 16733-85-0) be handled?
Waste containing 1,3-Thiazole-2-carboxamide (CAS: 16733-85-0) should be collecte...
What regulatory guidelines apply to 5-(Difluoromethyl)-2-fluorobenzonitrile (CAS: 934175-58-3)?
5-(Difluoromethyl)-2-fluorobenzonitrile (CAS: 934175-58-3) is subject to regulat...
How is Methyl 3-acetamido-2-thiophenecarboxylate (CAS: 22288-79-5) typically synthesized?
Methyl 3-acetamido-2-thiophenecarboxylate can be synthesized by the reaction of ...
What is 4-Isoquinolinecarbonitrile (CAS: 34846-65-6)?
4-Isoquinolinecarbonitrile is a chemical compound with the CAS number 34846-65-6...
How should Methyl 1H-1,2,3-triazole-4-carboxylate (CAS: 877309-59-6) be stored?
Store Methyl 1H-1,2,3-triazole-4-carboxylate (CAS: 877309-59-6) in a cool, dry p...
What regulatory guidelines apply to 6-Bromo[1,3]thiazolo[5,4-b]pyridin-2-amine (CAS: 1160791-13-8)?
6-Bromo[1,3]thiazolo[5,4-b]pyridin-2-amine (CAS: 1160791-13-8) is subject to the...
Is (2S,3S)-2-Ammonio-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate (CAS: 23651-95-8) safe?
(2S,3S)-2-Ammonio-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate (CAS: 23651-95-8) ...
What are the physical and chemical properties of 7-bromo-3-methyl-3,4-dihydroquinazolin-4-one (CAS: 1293987-84-4)?
7-Bromo-3-methyl-3,4-dihydroquinazolin-4-one is a solid with a crystalline form....
Source Journal
Chemical Communications

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry














