Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton
Literature Information
Publication Date
2004-04-14
DOI
10.1039/B402925A
Impact Factor
6.222
Authors
Ji Ma, Sidney M. Hecht
View Original
Abstract
Bioassay-guided fractionation of an extract prepared from Alangium javanicum using an assay to monitor Cu2+-dependent DNA strand scission led to the isolation of javaniside, a new type of oxindole glycoside.
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Source Journal
Chemical Communications
CiteScore:
8.6
Self-citation Rate:
4.7%
Articles per Year:
2458
ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry
Recommended Compounds
![(1R,5R)-3-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid structure](https://static.chemtradehub.com/structs/116/1165450-63-4-bfe1.webp "(1R,5R)-3-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid structure")
(1R,5R)-3-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS Number:
1165450-63-4
Molecular Formula:
C11H17NO4
5-(2-Methyl-3-furyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS Number:
346464-59-3
Molecular Formula:
C13H11N3OS
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