Cyclopropyl fatty acids implicate a radical but not a cation as an intermediate in P450BM3-catalysed hydroxylations
Literature Information
Max J. Cryle, Julia M. U. Stuthe, Paul R. Ortiz de Montellano, James J. De Voss
Novel cyclopropyl containing fatty acids are good substrates for P450BM3 catalysed hydroxylation and analysis of their oxidation products indicates the presence of a radical intermediate (maximum rebound rate 2.6 × 1010 s−1) and the absence of any cationic intermediate.
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