Facile protocol for the highly regioselective and stereodivergent synthesis of substituted bishomoallylic alcohols from esters

Literature Information

Publication Date 2004-02-17
DOI 10.1039/B315758J
Impact Factor 6.222
Authors

Martin Oestreich, Fernando Sempere-Culler


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Abstract

Regio- and diastereoselective preparation of bishomoallylic alcohols was realized by a facile four-step protocol including α,α′-selective zinc-mediated bispropargylation of unactivated esters and stereoselective reduction of the resulting bishomopropargylic alcohols.

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