A direct meta-lithiation route to 1,3-disubstituted ferrocenes

Literature Information

Publication Date 2004-02-10
DOI 10.1039/B314641C
Impact Factor 6.222
Authors

Christophe Pichon, Barbara Odell, John M. Brown


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Abstract

Ferrocenyl sulfides afford meta-lithiation products with up to 94% regioselectivity on reaction with s-BuLi; the resulting 1,3-disubstituted ferrocenes can then be reacted with a variety of electrophiles.

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