The Sonogashira coupling reaction catalyzed by ultrafine nickel(0) powder

Literature Information

Publication Date 2004-01-27
DOI 10.1039/B314246A
Impact Factor 6.222
Authors

Pinhua Li, Yicheng Zhang


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Abstract

The Sonogashira coupling reaction catalyzed by ultrafine nickel(0) powder has been developed; terminal alkynes couple with aryl, alkenyl iodide and aryl bromide in the presence of cuprous iodide, triphenylphosphine, potassium hydroxide and ultrafine particle nickel(0) to provide the corresponding cross-coupling products with high yields.

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