Aziridinyl anions from a chiral, nonracemic 2-isopropylidineaziridine: surprisingly diastereoselective alkylation reactions

Literature Information

Publication Date 2003-05-20
DOI 10.1039/B303252C
Impact Factor 6.222
Authors

J. F. Hayes, N. Prévost, I. Prokeš, M. Shipman, A. M. Z. Slawin, H. Twin


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Abstract

Lithiation and alkylation of a 2-isopropylidineaziridine bearing an (S)-α-methylbenzyl group on nitrogen proceeds with high levels of diastereocontrol (80–90% de).

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