Structures and phase transitions in aqueous dispersions of branched-chain glycerophosphoethanolamines

Literature Information

Publication Date 2000-09-18
DOI 10.1039/B003516P
Impact Factor 3.676
Authors

Frank Bringezu, Gert Rapp, Bodo Dobner, Peter Nuhn, Gerald Brezesinski


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Abstract

Glycerophosphoethanolamines with α-branched fatty acids were synthesized, varying the side-chain length. Differential scanning calorimetry and X-ray diffraction were applied to investigate the influence of the chemical alteration on the physico-chemical parameters and the structures formed in lipid–water dispersions. The results show that the introduction and stepwise elongation of side-chains decrease the transition temperature from gel to liquid-crystalline phases. The Tm values pass through a minimum and increase slightly on going to the triple-chain lipid. The change in the transition parameters is connected with a modified polymorphism. Short side-chains induce a tilt in the gel state and the elongation of the branch leads to interdigitated gel phases. With increasing side-chain length, non-lamellar liquid-crystalline phases are stabilized. For the long-branched derivative, an interdigitation of head-groups from adjacent bilayers is proposed.

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Source Journal

Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
CiteScore: 5.5
Self-citation Rate: 10.3%
Articles per Year: 3036

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.

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