6-Methyl-2-piperidinecarboxylic acid

Basic Information

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CAS Number

99571-58-1

Molecular Formula

C7H13NO2

Molecular Weight

143.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Boiling Point

266.996 °C at 760 mmHg

Density

1.063

Flash Point

266.996 °C at 760 mmHg

Refractive Index

1.465

SMILES

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CC1CCCC(N1)C(=O)O

InChI

InChI=1S/C7H13NO2/c1-5-3-2-4-6(8-5)7(9)10/h5-6,8H,2-4H2,1H3,(H,9,10)

InChIKey

IHLDCUQUFBWSJU-UHFFFAOYSA-N

LogP

0.6016000000000001

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

136

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

6-methyl-2-Piperidinecarboxylic acid
99571-58-1
BB 0260997
6-methylpiperidine-2-carboxylic acid*
MFCD00513436
AB01332249-02
6-METHYLPIPERDINE-2-CARBOXYLICACID
SB43088
NCGC00339407-01
6-methylpiperidine-2-carboxylic acid
AH-262/01729056
2-Piperidinecarboxylic acid, 6-methyl-
AC-23277
DTXSID40902716
FT-0682663
6-methylpipecolic acid
EN300-152086
DS-15376
CS-0039203
6-Methyl-2-piperidine carboyxlic acid
6-methylpiperidine-2-carboxylicacid
AKOS005258601
CHEBI:194380
IHLDCUQUFBWSJU-UHFFFAOYSA-N
6-METHYL-2-PIPERIDINE CARBOXYLIC ACID
SCHEMBL5955767
NoName_3265
6-Methyl-piperidine-2-carboxylic acid
CL3106
6-Methylpiperidine-2-carboxylic acid
6-METHYL-2-PIPERIDINE CARBOYXLIC ACID

MDL Number

MFCD00513436

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Methyl-2-piperidinecarboxylic acid (CAS: 99571-58-1)?

6-Methyl-2-piperidinecarboxylic acid is a white crystalline solid with a molecular weight of approximately 147.19 g/mol. It has a solubility of 200 mg/L in water and is moderately soluble in organic solvents. The compound is mildly acidic and exhibits limited reactivity, particularly in the presence of basic compounds.

How is 6-Methyl-2-piperidinecarboxylic acid (CAS: 99571-58-1) typically synthesized?

6-Methyl-2-piperidinecarboxylic acid is typically synthesized via a multistep process, starting from n-pentylamine and acetic anhydride. The reaction involves an acylation step followed by amination to introduce the methyl group. The process requires the use of anhydrous conditions and appropriate catalysts to achieve good selectivity and yield.

What industries use 6-Methyl-2-piperidinecarboxylic acid (CAS: 99571-58-1)?

6-Methyl-2-piperidinecarboxylic acid is used in various industries. It is commonly employed in pharmaceuticals as a precursors for drug synthesis, in polymers for its solubility and reactivity properties, and in sensors for detection purposes. Additionally, it has applications in the production of semiconductors and other electronic materials.

What precautions should be taken when handling 6-Methyl-2-piperidinecarboxylic acid (CAS: 99571-58-1)?

When handling 6-Methyl-2-piperidinecarboxylic acid, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood to minimize inhalation risks. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.