4-Phenylmorpholine | CAS No. 92-53-5

Q: What regulatory guidelines apply to 4-Phenylmorpholine (CAS: 92-53-5)?

4-Phenylmorpholine (CAS: 92-53-5) falls under several regulatory guidelines. It is classified under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) as a category 4 sensitiser. For European markets, it must comply with REACH regulations, which require registration, evaluation, and authorization for certain substances. In the US, FDA and EPA regulations apply, particularly for pharmaceutical and agricultural applications, requiring appropriate documentation and handling procedures.

Q: Are there alternatives to 4-Phenylmorpholine (CAS: 92-53-5) in synthesis?

There are several alternatives to 4-Phenylmorpholine (CAS: 92-53-5) in synthesis, including 3-Methylmorpholine, Pyrrolidine, and p-Toluidine. These alternatives offer similar functionalities but may differ in reactivity and toxicity, providing flexibility in chemical synthesis depending on the specific requirements of the reaction.

Q: What is the market or research trend for 4-Phenylmorpholine (CAS: 92-53-5)?

The market for 4-Phenylmorpholine (CAS: 92-53-5) is primarily driven by its use in pharmaceuticals, particularly in the development of antispasmodic and anti-inflammatory drugs. Research trends are shifting towards the development of more sustainable and less toxic alternatives. However, due to its unique properties, it remains a valuable compound in various chemical research areas, including drug discovery and functional material development.

Q: How should waste containing 4-Phenylmorpholine (CAS: 92-53-5) be handled?

Waste containing 4-Phenylmorpholine (CAS: 92-53-5) should be collected in sealed containers and stored in a secure, well-ventilated area. Disposal should be handled by a professional waste management company that specializes in hazardous waste. Proper protective equipment, such as gloves and goggles, should be worn during handling. Environmental protection measures include ensuring that no waste is released into water sources or the air. Compliance with local, national, and international regulations is crucial.

4-Phenylmorpholine

Basic Information

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CAS Number

92-53-5

Molecular Formula

C10H13NO

Molecular Weight

163.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

52.0 to 59.0 deg-C

Boiling Point

270°C

Density

1.053 g/cm3 (60℃)

Water Solubility

3.46 g/L

Solubility

3.46 g/L

Refractive Index

1.5400 (estimate)

Vapor Pressure

<0.1 mmHg ( 20 °C)

SMILES

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C1COCCN1C2=CC=CC=C2

InChI

InChI=1S/C10H13NO/c1-2-4-10(5-3-1)11-6-8-12-9-7-11/h1-5H,6-9H2

InChIKey

FHQRDEDZJIFJAL-UHFFFAOYSA-N

LogP

1.5231999999999997

Topological Polar Surface Area

12.47 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

126

Safety Information

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GHS Hazard Pictograms

H302

H311

H319

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1(b) Class 6.1(b)

Synonyms & References

English

H4OC7FB1EX
UNII-H4OC7FB1EX
P0196
Phenylmorpholine
MORPHOLINE, 4-PHENYL-
NSC2628
Phenyl morpholine
NSC 2628
92-53-5
DTXSID8059057
AKOS003398235
SY003877
AMY2650
CS-W014318
AI3-01091
NS00022878
NSC-239125
SR-01000514391
N-Phenylmorpholine
4-Phenylmorpholine
4-Phenyl-morpholine
FT-0619409
SY246296
EINECS 202-164-0
MFCD31699968
Q27279634
CHEMBL4435329
MFCD00006166
NSC-2628
4-phenylmorpholin
BRN 0132159

MDL Number

MFCD00006166

Customs Code

29349990

FAQ

What regulatory guidelines apply to 4-Phenylmorpholine (CAS: 92-53-5)?

4-Phenylmorpholine (CAS: 92-53-5) falls under several regulatory guidelines. It is classified under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) as a category 4 sensitiser. For European markets, it must comply with REACH regulations, which require registration, evaluation, and authorization for certain substances. In the US, FDA and EPA regulations apply, particularly for pharmaceutical and agricultural applications, requiring appropriate documentation and handling procedures.

Are there alternatives to 4-Phenylmorpholine (CAS: 92-53-5) in synthesis?

There are several alternatives to 4-Phenylmorpholine (CAS: 92-53-5) in synthesis, including 3-Methylmorpholine, Pyrrolidine, and p-Toluidine. These alternatives offer similar functionalities but may differ in reactivity and toxicity, providing flexibility in chemical synthesis depending on the specific requirements of the reaction.

What is the market or research trend for 4-Phenylmorpholine (CAS: 92-53-5)?

The market for 4-Phenylmorpholine (CAS: 92-53-5) is primarily driven by its use in pharmaceuticals, particularly in the development of antispasmodic and anti-inflammatory drugs. Research trends are shifting towards the development of more sustainable and less toxic alternatives. However, due to its unique properties, it remains a valuable compound in various chemical research areas, including drug discovery and functional material development.

How should waste containing 4-Phenylmorpholine (CAS: 92-53-5) be handled?

Waste containing 4-Phenylmorpholine (CAS: 92-53-5) should be collected in sealed containers and stored in a secure, well-ventilated area. Disposal should be handled by a professional waste management company that specializes in hazardous waste. Proper protective equipment, such as gloves and goggles, should be worn during handling. Environmental protection measures include ensuring that no waste is released into water sources or the air. Compliance with local, national, and international regulations is crucial.