1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone(CAS: 90734-71-7)

1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone is a crystalline solid with a molecular weight of approximately 292.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like DMSO and DMF. This compound is highly reactive and can undergo various chemical transformations under specific conditions.

1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone is often synthesized via a multi-step process involving the condensation of 6-chloroimidazo[1,2-b]pyridazine with acetyl chloride, followed by reduction of the ketone functionality. The synthesis typically requires the use of a catalyst such as sodium triacetoxyborohydride, and the process achieves good yield with high selectivity.

1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone is utilized in the pharmaceutical industry for its potential as an intermediate in the synthesis of bioactive compounds. It also finds applications in the development of sensors and materials for semiconductors.

When handling 1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to prevent inhalation of fumes. In case of a spill, absorb with paper towels and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.