Methyl 5-cyano-1-benzofuran-2-carboxylate | CAS No. 84102-77-2
Methyl 5-cyano-1-benzofuran-2-carboxylate
Basic Information
CAS Number
84102-77-2
Molecular Formula
C11H7NO3
Molecular Weight
190.2 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Methyl 5-cyanobenzofuran-2-carboxylate
- METHYL 5-CYANO-1-BENZOFURAN-2-CARBOXYLATE
- FT-0734660
- 84102-77-2
- AKOS002666486
- SCHEMBL9231951
- AC-27187
- Methyl5-cyanobenzofuran-2-carboxylate
- A904324
- DTXSID10442073
- Methyl 5-cyano-1-benzofuran-2-carboxylate
MDL Number
MFCD08753860
FAQ
What are the physical and chemical properties of Methyl 5-cyano-1-benzofuran-2-carboxylate (CAS: 84102-77-2)?
Methyl 5-cyano-1-benzofuran-2-carboxylate (CAS: 84102-77-2) has a crystalline form with a molecular weight of approximately 222.17 g/mol. It is slightly soluble in common organic solvents such as methanol and chloroform. The compound is reactive towards nucleophiles and can undergo various transformations in organic reactions. It is also sensitive to moisture and air, requiring storage under inert conditions.
How is Methyl 5-cyano-1-benzofuran-2-carboxylate (CAS: 84102-77-2) typically synthesized?
Methyl 5-cyano-1-benzofuran-2-carboxylate (CAS: 84102-77-2) is synthesized via the condensation of 2-benzofuranone and cyanoacetic acid methyl ester using an appropriate coupling agent. The synthesis involves the use of a base and can be optimized for better yield and selectivity. The reaction typically proceeds under mild conditions, and the product is isolated by recrystallization.
What industries use Methyl 5-cyano-1-benzofuran-2-carboxylate (CAS: 84102-77-2)?
Methyl 5-cyano-1-benzofuran-2-carboxylate (CAS: 84102-77-2) is used in the pharmaceutical industry for the synthesis of certain intermediates and drug candidates. It also finds applications in the polymer industry for the modification of polymer properties and in the electronic industry for the production of semiconductors and sensors.
What precautions should be taken when handling Methyl 5-cyano-1-benzofuran-2-carboxylate (CAS: 84102-77-2)?
When handling Methyl 5-cyano-1-benzofuran-2-carboxylate (CAS: 84102-77-2), it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, dry place away from moisture and strong oxidizing agents. In case of a spill, it should be cleaned up using appropriate procedures and materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.
Related Compounds
![[1-(2-Pyrazinylmethyl)-4-piperidinyl]methanol structure](https://static.chemtradehub.com/structs/124/1247703-29-2-3e8f.webp "[1-(2-Pyrazinylmethyl)-4-piperidinyl]methanol structure")
![(2S)-2-Amino-3-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-1-propanol structure](https://static.chemtradehub.com/structs/139/139264-69-0-da9c.webp "(2S)-2-Amino-3-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-1-propanol structure")
(2S)-2-Amino-3-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-1-propanol
CAS Number:
139264-69-0
Molecular Formula:
C15H23N3O
![2-[(1S)-3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate (2E)-2-butenedioate (1:1) structure](https://static.chemtradehub.com/structs/143/1431511-18-0-164b.webp "2-[(1S)-3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate (2E)-2-butenedioate (1:1) structure")
2-[(1S)-3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate (2E)-2-butenedioate (1:1)
CAS Number:
1431511-18-0
Molecular Formula:
C30H41NO7
![3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one structure](https://static.chemtradehub.com/structs/144/144486-08-8-1df1.webp "3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one structure")
3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one
CAS Number:
144486-08-8
Molecular Formula:
C11H9N3O
![(1aS,1bS,6bS,7aS,8aS,9R,10S,11S,11aS)-9,10,11-Trihydroxy-10-isopropyl-1b-methyl-1b,3,6,6b,7,7a,9,10,11,11a-decahydrobisoxireno[8a,9:4b,5]phenanthro[1,2-c]furan-4(2H)-one structure](https://static.chemtradehub.com/structs/147/147852-78-6-0a74.webp "(1aS,1bS,6bS,7aS,8aS,9R,10S,11S,11aS)-9,10,11-Trihydroxy-10-isopropyl-1b-methyl-1b,3,6,6b,7,7a,9,10,11,11a-decahydrobisoxireno[8a,9:4b,5]phenanthro[1,2-c]furan-4(2H)-one structure")
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