3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) | CAS No. 760988-03-2

3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid)

Basic Information

CAS Number

760988-03-2

Molecular Formula

C24H17FO6

Molecular Weight

420.39 g/mol

AD

Basic Physical Properties

C1=CC(=C(C=C1/C=C/C2=CC(=C(C=C2)O)C(=O)O)F)/C=C/C3=CC(=C(C=C3)O)C(=O)O

InChI

InChI=1S/C24H17FO6/c25-20-13-16(2-1-14-5-9-21(26)18(11-14)23(28)29)4-8-17(20)7-3-15-6-10-22(27)19(12-15)24(30)31/h1-13,26-27H,(H,28,29)(H,30,31)/b2-1+,7-3+

InChIKey

DZXZHGCGNRRJEG-WMWQKROPSA-N

LogP

4.974100000000004

Topological Polar Surface Area

115.06000000000002 Ų

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

692

Synonyms & References

English

  • Benzoic acid, 3,3'-[(2-fluoro-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis[6-hydroxy-
  • 1-Fluoro-2,5-bis[(E)-3-carboxy-4-hydroxystyryl]benzene solution
  • 3,3′-[(2-Fluoro-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis[6-hydroxybenzoic acid] solution
  • FSB
  • 1-fluoro-2,5-bis(3-carboxy-4-hydroxystyryl)benzene
  • (E,E)-1-Fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene
  • (1-fluoro-2,5-bis[(e)-3-carboxy-4-hydroxystyryl]benzene)
  • 1-Fluoro-2,5-bis[(E)-3-carboxy-4-hydroxystyryl]benzene
  • FSB staining solution, 1 % (w/v) in DMSO, fluorescent stain for amyloid

MDL Number

MFCD28902305

FAQ

What are the physical and chemical properties of 3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) (CAS: 760988-03-2)?

3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) (CAS: 760988-03-2) is a crystalline solid with a molecular weight of approximately 492.2 g/mol. It has a melting point around 305-307°C and is moderately soluble in water. Chemically, it is highly reactive due to the presence of hydroxy and fluoro groups, making it suitable for various derivatization reactions.

How is 3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) (CAS: 760988-03-2) typically synthesized?

3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) can be synthesized via multistep reactions involving the condensation of 2-fluorobenzoic acid with diacetylene compounds, followed by electrophilic addition and ring closure. The synthesis typically requires mild heat and the use of a catalyst such as palladium(0) to achieve high selectivity and yield.

What industries use 3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) (CAS: 760988-03-2)?

3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) is primarily used in the pharmaceutical and polymer industries for the development of advanced materials and drug candidates. It also finds applications in the production of sensors and semiconductors due to its unique chemical structure.

What precautions should be taken when handling 3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) (CAS: 760988-03-2)?

When handling 3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles, as it is reactive and can cause irritation. Handle it in a well-ventilated area or fume hood. In case of spill, immediately clean up with absorbent materials and follow local waste disposal regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.

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