3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid)(CAS: 760988-03-2)

3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) (CAS: 760988-03-2) is a crystalline solid with a molecular weight of approximately 492.2 g/mol. It has a melting point around 305-307°C and is moderately soluble in water. Chemically, it is highly reactive due to the presence of hydroxy and fluoro groups, making it suitable for various derivatization reactions.

3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) can be synthesized via multistep reactions involving the condensation of 2-fluorobenzoic acid with diacetylene compounds, followed by electrophilic addition and ring closure. The synthesis typically requires mild heat and the use of a catalyst such as palladium(0) to achieve high selectivity and yield.

3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid) is primarily used in the pharmaceutical and polymer industries for the development of advanced materials and drug candidates. It also finds applications in the production of sensors and semiconductors due to its unique chemical structure.

When handling 3,3'-[(2-Fluoro-1,4-phenylene)di(E)-2,1-ethenediyl]bis(6-hydroxybenzoic acid), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles, as it is reactive and can cause irritation. Handle it in a well-ventilated area or fume hood. In case of spill, immediately clean up with absorbent materials and follow local waste disposal regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.