(3S)-Tetrahydro-2H-pyran-3-ol

Basic Information

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CAS Number

72886-97-6

Molecular Formula

C5H10O2

Molecular Weight

102.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

189.4±8.0°C at 760 mmHg

SMILES

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C1CC(COC1)O

InChI

InChI=1S/C5H10O2/c6-5-2-1-3-7-4-5/h5-6H,1-4H2/t5-/m0/s1

InChIKey

BHDLTOUYJMTTTM-YFKPBYRVSA-N

LogP

0.1577

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-TETRAHYDRO-2H-PYRAN-3-OL
SCHEMBL14429808
DTXSID20482682
AKOS008901071
DS-15946
MFCD09753060
P10755
2H-Pyran-3-ol, tetrahydro-, (S)-
(3S)-OXAN-3-OL
72886-97-6
CS-W007290
(S)-Tetrahydro-2H-pyran-3-ol
(3S)-oxan-3-ol
RW3618
S-3-hydroxytetrahydropyran
PubChem24399
FCH869970
RL04773
SB16021
AX8220626
(3S)-tetrahydropyran-3-ol

MDL Number

MFCD09753060

Customs Code

2932999099

FAQ

What are the physical and chemical properties of (3S)-Tetrahydro-2H-pyran-3-ol (CAS: 72886-97-6)?

(3S)-Tetrahydro-2H-pyran-3-ol is a colorless to white crystalline solid with a molecular weight of approximately 112.11 g/mol. It has a faint, sweet odor and is soluble in water, ethanol, and ether. It is mildly acidic and can undergo reactions such as esterification and reduction. This compound is often used as a precursor in organic synthesis due to its reactive nature.

How is (3S)-Tetrahydro-2H-pyran-3-ol (CAS: 72886-97-6) typically synthesized?

(3S)-Tetrahydro-2H-pyran-3-ol can be synthesized by the reduction of (3S)-tetrahydro-2H-pyranone using lithium aluminum hydride (LAH) as a catalyst. This process provides good yields and selectivity. Other methods include the hydrogenation of 1,3-dioxane-2,5-dione followed by reduction using sodium borohydride.

What industries use (3S)-Tetrahydro-2H-pyran-3-ol (CAS: 72886-97-6)?

(3S)-Tetrahydro-2H-pyran-3-ol is widely used in the pharmaceutical, polymer, and chemical industries. It is a key intermediate in the synthesis of various drugs and medicinals. Additionally, it serves as a building block in the production of polymers and is utilized in the development of sensors and semiconductors.

What precautions should be taken when handling (3S)-Tetrahydro-2H-pyran-3-ol (CAS: 72886-97-6)?

When handling (3S)-Tetrahydro-2H-pyran-3-ol, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be carried out in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents and proper disposal methods. Refer to the Safety Data Sheet (SDS) for detailed guidelines on handling and storage.