2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine | CAS No. 627536-09-8
2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine
Basic Information
CAS Number
627536-09-8
Molecular Formula
C17H10ClFN6
Molecular Weight
352.76 g/mol
AD
Basic Physical Properties
Density
1.487
Solubility
DMSO: >5mg/mL
Safety Information
View Safety InformationGHS Hazard Pictograms
H302Hazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
Synonyms & References
English
- SD 208
- SD-208
- 2-(5-Chloro-2-fluorophenyl)-4-[(4-pyridyl)amino]pteridine
- 2-(5-chloro-2-fluorophenyl)-N-pyridin-4-ylpteridin-4-amine
- 2-[(5-CHLORO-2-FLUOROPHENYL)PTERIDIN-4-YL]PYRIDIN-4-YL-AMINE
- 4-Pteridinamine, 2-(5-chloro-2-fluorophenyl)-N-4-pyridinyl-
- ALK5 Inhibitor V
- 2-(5-Chloro-2-fluorophenyl)pteridin-4-yl]pyridin-4-yl-amine
- 2-(5-Chloro-2-fluorophenyl)-N-4-pyridinyl-4-pteridinamine
- SD208
- 2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine
- 2-(5-Chloro-2-fluorophenyl)pteridin-4-yl)pyridin-4-yl amine
- Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor V
- [2-(5-Chloro-2-fluoro-phenyl)-pteridin-4-yl]-pyridin-4-yl-amine
- C17H10ClFN6
- MLS006010305
- GTPL824
MDL Number
MFCD11519969
FAQ
What are the physical and chemical properties of 2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine (CAS: 627536-09-8)?
2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine is a crystalline compound with a molecular weight of approximately 423.14 g/mol. It has a pKa of about 5.0 and is poorly soluble in water, but soluble in common organic solvents. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored in a dry, cool place to avoid hydrolysis.
How is 2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine (CAS: 627536-09-8) typically synthesized?
2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine is typically synthesized via multistep reactions involving electrophilic aromatic substitution and condensation reactions. The synthesis involves the use of common organic solvents and catalysts. The yield is moderate, around 50-70%, and the method is selective for the desired product. Detailed procedures can be found in the literature.
What industries use 2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine (CAS: 627536-09-8)?
2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine is used in the pharmaceutical industry for the development of potential anti-inflammatory and anticancer drugs. It is also explored in the chemical sensing sector for its ability to detect specific ions and organic molecules. Limited applications in polymers and semiconductors are also reported, but its primary focus is on pharmaceutical and sensing applications.
What precautions should be taken when handling 2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine (CAS: 627536-09-8)?
When handling 2-(5-Chloro-2-fluorophenyl)-N-(4-pyridinyl)-4-pteridinamine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. In case of a spill, immediately clean up the spill with appropriate absorbent materials and report it to a supervisor. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.
Related Compounds
![[1-(2-Pyrazinylmethyl)-4-piperidinyl]methanol structure](https://static.chemtradehub.com/structs/124/1247703-29-2-3e8f.webp "[1-(2-Pyrazinylmethyl)-4-piperidinyl]methanol structure")
![(2S)-2-Amino-3-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-1-propanol structure](https://static.chemtradehub.com/structs/139/139264-69-0-da9c.webp "(2S)-2-Amino-3-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-1-propanol structure")
(2S)-2-Amino-3-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-1-propanol
CAS Number:
139264-69-0
Molecular Formula:
C15H23N3O
![2-[(1S)-3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate (2E)-2-butenedioate (1:1) structure](https://static.chemtradehub.com/structs/143/1431511-18-0-164b.webp "2-[(1S)-3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate (2E)-2-butenedioate (1:1) structure")
2-[(1S)-3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl 2-methylpropanoate (2E)-2-butenedioate (1:1)
CAS Number:
1431511-18-0
Molecular Formula:
C30H41NO7
![3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one structure](https://static.chemtradehub.com/structs/144/144486-08-8-1df1.webp "3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one structure")
3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one
CAS Number:
144486-08-8
Molecular Formula:
C11H9N3O
![(1aS,1bS,6bS,7aS,8aS,9R,10S,11S,11aS)-9,10,11-Trihydroxy-10-isopropyl-1b-methyl-1b,3,6,6b,7,7a,9,10,11,11a-decahydrobisoxireno[8a,9:4b,5]phenanthro[1,2-c]furan-4(2H)-one structure](https://static.chemtradehub.com/structs/147/147852-78-6-0a74.webp "(1aS,1bS,6bS,7aS,8aS,9R,10S,11S,11aS)-9,10,11-Trihydroxy-10-isopropyl-1b-methyl-1b,3,6,6b,7,7a,9,10,11,11a-decahydrobisoxireno[8a,9:4b,5]phenanthro[1,2-c]furan-4(2H)-one structure")
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