(2-Methoxy-5-methylphenyl)acetic acid | CAS No. 58506-24-4

(2-Methoxy-5-methylphenyl)acetic acid

Basic Information

CAS Number

58506-24-4

Molecular Formula

C10H12O3

Molecular Weight

180.2 g/mol

AD

Basic Physical Properties

COc1ccc(C)cc1CC(=O)O

InChI

InChI=1S/C10H12O3/c1-7-3-4-9(13-2)8(5-7)6-10(11)12/h3-5H,6H2,1-2H3,(H,11,12)

InChIKey

GHVGGBAEPWMNGB-UHFFFAOYSA-N

LogP

1.63072

Topological Polar Surface Area

46.53 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Synonyms & References

English

  • 2-Methoxy-5-methylphenylacetic acid
  • (2-METHOXY-5-METHYLPHENYL)ACETIC ACID
  • (2-Methoxy-5-methyl-phenyl)-acetic acid
  • 2-(2-methoxy-5-methylphenyl)acetate
  • 2-(2-methoxyphenyl)acetic acid
  • (2-Methoxy-5-methyl-phenyl)-essigsaeure
  • 2-methoxy-5-methylbenzeneacetic acid
  • 2-Methoxy-5-methylphenylessigsaeure
  • 2-Methoxy-5-methyl-phenylessigsaeure
  • 3-Methyl-6-methoxyphenylessigsaeure
  • Nsc30128
  • 2-(2-methoxy-5-methylphenyl)acetic acid

MDL Number

MFCD06653293

FAQ

What are the physical and chemical properties of (2-Methoxy-5-methylphenyl)acetic acid (CAS: 58506-24-4)?

(2-Methoxy-5-methylphenyl)acetic acid has a crystalline form, a molecular weight of approximately 204.26 g/mol, and a solubility of about 10 g/L in water. It is a weak acid with a pKa of around 4.5. The compound is generally stable under normal conditions but may react with strong bases or oxidizing agents.

How is (2-Methoxy-5-methylphenyl)acetic acid (CAS: 58506-24-4) typically synthesized?

(2-Methoxy-5-methylphenyl)acetic acid is usually synthesized via the condensation of (2-methoxy-5-methylphenyl)acetyl chloride with sodium acetate in the presence of a catalytic amount of triethylamine. The reaction is conducted under anhydrous conditions to achieve high selectivity and yield.

What industries use (2-Methoxy-5-methylphenyl)acetic acid (CAS: 58506-24-4)?

(2-Methoxy-5-methylphenyl)acetic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the chemical industry for the production of polymers and as a reagent in various analytical techniques.

What precautions should be taken when handling (2-Methoxy-5-methylphenyl)acetic acid (CAS: 58506-24-4)?

When handling (2-Methoxy-5-methylphenyl)acetic acid, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up immediately with appropriate absorbent materials, and the area should be flushed with water. Always refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for specific safety guidelines.

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