2,2-diphenylacetamide

Basic Information

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CAS Number

4695-13-0

Molecular Formula

C14H13NO

Molecular Weight

211.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

164-167°C

SMILES

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C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)N

InChI

InChI=1S/C14H13NO/c15-14(16)13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13H,(H2,15,16)

InChIKey

ZXQVXEAZKZFEEP-UHFFFAOYSA-N

LogP

2.3037999999999994

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

209

Synonyms & References

English

2,2-Diphenylacetamide
YZX41252DL
alpha,alpha-Diphenylacetamide
AKOS000294655
Cambridge id 5574564
HMS1583L12
Benzeneacetamide, alpha-phenyl-
2,2-Diphenylacetamid
UNII-YZX41252DL
MS-9496
Acetamide, 2,2-diphenyl-
.alpha.,.alpha.-Diphenylacetamide
Q27294808
Diphenylacetic acid amide
DIPHENYLACETIC ACID AMIDE [MI]
WLN: ZVYR&R
alpha-Phenylbenzeneacetamide
MFCD00025496
NSC29731
Benzeneacetamide, .alpha.-phenyl-
NSC 29731
BRN 1871583
SR-01000214162
SR-01000214162-1
AB01334897-02
DTXSID80196995
4695-13-0
4-09-00-02501 (Beilstein Handbook Reference)
FT-0609292
SCHEMBL741751
NCGC00343005-01

MDL Number

MFCD00025496

Customs Code

2924299090

FAQ

What are the physical and chemical properties of 2,2-diphenylacetamide (CAS: 4695-13-0)?

2,2-Diphenylacetamide (CAS: 4695-13-0) is a white crystalline solid with a molecular weight of approximately 248.35 g/mol. It is slightly soluble in water but more soluble in organic solvents such as ethanol, acetone, and chloroform. Chemically, it is moderately reactive, with limited reactivity towards bases and nucleophiles. It exhibits good thermal stability up to around 250°C.

How is 2,2-diphenylacetamide (CAS: 4695-13-0) typically synthesized?

2,2-Diphenylacetamide is typically synthesized by the amidation of acetic anhydride with diphenylamine under mild conditions. The reaction is catalyzed by a strong acid, such as concentrated sulfuric acid, in the presence of a solvent like benzene or toluene. The yield is generally high, and the method is well-suited for laboratory and industrial-scale production.

What industries use 2,2-diphenylacetamide (CAS: 4695-13-0)?

2,2-Diphenylacetamide (CAS: 4695-13-0) is used in various industries, including pharmaceuticals for its use as an intermediate in the synthesis of certain drugs, polymers for its role in the formation of certain plastic materials, and sensors for its application in the detection of specific chemicals. It is also utilized in the semiconductor industry for its properties in certain doping applications.

What precautions should be taken when handling 2,2-diphenylacetamide (CAS: 4695-13-0)?

When handling 2,2-diphenylacetamide (CAS: 4695-13-0), it is important to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. It should be handled in a fume hood to minimize inhalation risks. Spills should be handled by sweeping or vacuuming and disposing of waste in accordance with local regulations. Always refer to the safety data sheet (SDS) for specific handling instructions.