Ethyl L-norvalinate hydrochloride (1:1)

Basic Information

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CAS Number

40918-51-2

Molecular Formula

C7H16ClNO2

Molecular Weight

181.66 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

Solid

Melting Point

108.0 to 117.0 deg-C

Boiling Point

175.4°C at 760 mmHg

Flash Point

48.4°C

Specific Rotation

+8.0 to +10.0° (c=2, H2O)

SMILES

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CCCC(C(=O)OCC)N.Cl

InChI

InChI=1S/C7H15NO2.ClH/c1-3-5-6(8)7(9)10-4-2;/h6H,3-5,8H2,1-2H3;1H/t6-;/m0./s1

InChIKey

CHAJBHNQIZAJJM-RGMNGODLSA-N

LogP

1.0986999999999996

Topological Polar Surface Area

52.32 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

104

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Ethyl (S)-2-Aminovalerate Hydrochloride
H-Nva-OEt.HCl
(S)-2-Amino-pentanoic acid ethyl ester; hydrochloride
Ethyl (S)-2-Aminopentanoate Hydrochloride
L-Norvaline ethyl ester, HCl
CHAJBHNQIZAJJM-RGMNGODLSA-N
DTXSID50505010
MFCD08458628
HY-75949
(S)-Ethyl 2-aminopentanoate hydrochloride
A825345
H-Nva-OEt . HCl
(S)-2-Amino-pentanoic acid ethyl ester hydrochloride
GS-3204
Ethyl L-norvalinate--hydrogen chloride (1/1)
ethyl (2S)-2-aminopentanoate hydrochloride
N0898
AC-31122
ethyl (2S)-2-aminopentanoate;hydrochloride
AKOS015932639
SCHEMBL3185313
L-NORVALINE ETHYL ESTER HYDROCHLORIDE
(S)-2-Aminopentanoic Acid Ethyl Ester Hydrochloride
40918-51-2
L-Norvaline ethyl ester HCl
CS-M0539
(S)-2-Aminovaleric Acid Ethyl Ester Hydrochloride
O-Ethyl-L-norvaline Hydrochloride
AKOS015904719
L-Norvaline ethyl ester hydrochloride
ethyl (2S)-2-aminopentanoate,hydrochloride

MDL Number

MFCD08458628

FAQ

What are the physical and chemical properties of Ethyl L-norvalinate hydrochloride (CAS: 40918-51-2)?

Ethyl L-norvalinate hydrochloride is a crystalline compound with a molecular weight of approximately 271.69 g/mol. It has a high solubility in water and poor solubility in organic solvents. The compound is moderately reactive and may undergo hydrolysis under acidic or basic conditions. It is stable under normal storage conditions but should be protected from moisture and heat.

How is Ethyl L-norvalinate hydrochloride (CAS: 40918-51-2) typically synthesized?

Ethyl L-norvalinate hydrochloride is typically synthesized by the reaction of L-norvaline with ethyl chloroacetate in the presence of a base, such as sodium hydroxide. The reaction is generally carried out in an organic solvent like ethanol. The product is then isolated and crystallized from an aqueous solution. The yield of the reaction is around 90%, and the product can be obtained with good stereochemical control.

What industries use Ethyl L-norvalinate hydrochloride (CAS: 40918-51-2)?

Ethyl L-norvalinate hydrochloride is used in the pharmaceutical industry as a precursor for the synthesis of certain drugs. It is also utilized in the sensor industry for the development of gas sensors due to its specific chemical reactivity. Additionally, it can be used in the polymer industry as a monomer or for the modification of polymers.

What precautions should be taken when handling Ethyl L-norvalinate hydrochloride (CAS: 40918-51-2)?

When handling Ethyl L-norvalinate hydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information and guidelines.