4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide

Basic Information

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CAS Number

301836-41-9

Molecular Formula

C22H16N4O3

Molecular Weight

384.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Flash Point

354.4℃

Solubility

DMSO: 10 mg/mL, soluble

SMILES

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NC(=O)c1ccc(cc1)c1[nH]c(c(n1)c1ccc2c(c1)OCO2)c1ccccn1

InChI

InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)

InChIKey

FHYUGAJXYORMHI-UHFFFAOYSA-N

LogP

3.633300000000001

Topological Polar Surface Area

103.12000000000002 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

582

Synonyms & References

English

4-(4-(Benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide
SB431542
4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]Benzamide
SB-431542
SB431542 （SB-431542, SB 431542 ）
4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]benzamide
SB 431542
C22H16N4O3
E1557V1V0N
4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
4-(4-(1,3-Benzodioxole-5-yl)-5-(2-pyridyl)-1H-imidazole-2-yl)benzamide
4-[5-(1,3-Benzodioxol-5-Yl)-4-(Pyridin-2-Yl)-1h

MDL Number

MFCD05865244

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide (CAS: 301836-41-9)?

4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide is a crystalline solid with a molecular weight of approximately 414.28 g/mol. It has a low solubility in water but is soluble in organic solvents such as dichloromethane and ethanol. This compound exhibits moderate reactivity towards nucleophiles and is stable under neutral and acidic conditions. Its properties make it suitable for use in medicinal chemistry and drug development.

How is 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide (CAS: 301836-41-9) typically synthesized?

4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide is synthesized through multi-step reactions involving the coupling of 2-pyridinecarboxaldehyde, 1,3-benzenedicarbonitrile, and 2-aminobenzamide. The process involves the formation of an imidazole ring, followed by the introduction of the 1,3-benzo[d]oxole and pyridinyl substituents. The reaction is catalyzed by a palladium complex and typically yields pure products with high selectivity and good yield.

What industries use 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide (CAS: 301836-41-9)?

4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide is primarily used in the pharmaceutical industry for the development of antiviral and anti-inflammatory drugs. It is also of interest in the sensor and semiconductor industries due to its unique chemical properties. Its application in these industries highlights its potential for various scientific and technological advancements.

What precautions should be taken when handling 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide (CAS: 301836-41-9)?

When handling 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Ensure that the substance is handled in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up immediately using appropriate procedures, and all waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.

Related Compounds

Ethyl 3-amino-5-methyl-1H-pyrrole-2-carboxylate structure

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Compound Q&A

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Compound Q&A

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Compound Q&A

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Compound Q&A

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4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide | CAS No. 301836-41-9

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Flash Point

Solubility

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Synonyms & References

English

MDL Number

Customs Code

FAQ

What are the physical and chemical properties of 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide (CAS: 301836-41-9)?

How is 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide (CAS: 301836-41-9) typically synthesized?

What industries use 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide (CAS: 301836-41-9)?

What precautions should be taken when handling 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide (CAS: 301836-41-9)?

Related Compounds

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