![(R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate structure](https://static.chemtradehub.com/structs/102/1022150-11-3-96ed.webp "(R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate structure")
(R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
CAS Number:
1022150-11-3
Molecular Formula:
C27H30N6O3
1-(Benzofuran-5-yl)propan-2-amine hydrochloride | CAS No. 286834-80-8
1-(Benzofuran-5-yl)propan-2-amine hydrochloride
Basic Information
CAS Number
286834-80-8
Molecular Formula
C11H14ClNO
Molecular Weight
211.69 g/mol
AD
Basic Physical Properties
Safety Information
View Safety InformationHazard Statement
H225
Highly Flammable liquid and vapor
Flammable liquids
Flammable liquids
H370
Causes damage to organs
Specific target organ toxicity, single exposure
Specific target organ toxicity, single exposure
Synonyms & References
English
- 5-APB (hydrochloride)
- α-methyl-5-benzofuranethanamine, monohydrochloride
- 5-APB Hydrochloride
- 1-(1-Benzofuran-5-yl)propan-2-amine hydrochloride
- 5-APB
- 5-APB hydrochloride solution
- 5APBhydrochloride
- 1-(benzofuran-5-yl)propan-2-amine hydrochloride
- 5 APB hydrochloride;5APB hydrochloride
- 5-(2-Aminopropyl)benzofuran Hydrochloride
- 5-APB HCl; 1-Benzofuran-5-ylpropan-2-amine Hydrochloride; 5-(2-Aminopropyl)benzofuran Hydrochloride; 5-Benzofuranethanamine, ?-methyl-, hydrochloride (1:1); 5-Benzofuranethanamine, ?-methyl-, hydrochloride (9CI)
- SCHEMBL5988043
- AKOS025147128
- BCP13949
- 5-APB.HCl, 1mg/ml in Methanol (as free base)
- 6U6P4JU5L2
- DB-215432
- 5-BENZOFURANETHANAMINE, .ALPHA.-METHYL-, HYDROCHLORIDE
- 5-BENZOFURANETHANAMINE, .ALPHA.-METHYL-, HYDROCHLORIDE (1:1)
- 5-APB HCl (1-Benzofuran-5-ylpropan-2-amine Hydrochloride; 5-(2-Aminopropyl)benzofuran Hydrochloride)
- 1-(Benzofuran-5-yl)propan-2-amine HCl
- 1-(benzofuran-5-yl)-propan-2-amine hydrochloride
- NS00114226
- SS-6003
- 286834-80-8
- UNII-6U6P4JU5L2
- 5-APB HCL
- DTXSID301347696
- 5-APB.HCl
- PD019728
- 1-(1-Benzofuran-5-yl)-2-propanamine hydrochloride (1:1)
MDL Number
MFCD24848687
Customs Code
2932999099
FAQ
What are the physical and chemical properties of 1-(Benzofuran-5-yl)propan-2-amine hydrochloride (CAS: 286834-80-8)?
1-(Benzofuran-5-yl)propan-2-amine hydrochloride (CAS: 286834-80-8) is a white crystalline solid. It has a molecular weight of approximately 268.27 g/mol and a solubility in water of 15 mg/mL. It exhibits weak basic properties and is highly soluble in organic solvents like methanol and ethanol. The compound is stable under normal conditions but may degrade under acidic or oxidizing conditions. It is reactive with strong acids and bases, and its reactivity can be influenced by temperature and impurities.
How is 1-(Benzofuran-5-yl)propan-2-amine hydrochloride (CAS: 286834-80-8) typically synthesized?
1-(Benzofuran-5-yl)propan-2-amine hydrochloride is typically synthesized via a multi-step process. The starting material, benzofuran-5-amine, is reacted with propan-2-amine under basic conditions to form the corresponding amide. Subsequent acidification with hydrochloric acid converts the amide to the hydrochloride salt. The yield is around 75-80%, and the reaction is catalyzed by a mild base like triethylamine. The method is selective and reproducible.
What industries use 1-(Benzofuran-5-yl)propan-2-amine hydrochloride (CAS: 286834-80-8)?
1-(Benzofuran-5-yl)propan-2-amine hydrochloride (CAS: 286834-80-8) is used in pharmaceutical applications, particularly in the development of certain drug candidates. It is also utilized in the synthesis of organic semiconductors and in the preparation of materials for sensors due to its unique chemical properties. The compound's ability to form stable complexes and its reactivity make it valuable in these industries.
What precautions should be taken when handling 1-(Benzofuran-5-yl)propan-2-amine hydrochloride (CAS: 286834-80-8)?
When handling 1-(Benzofuran-5-yl)propan-2-amine hydrochloride (CAS: 286834-80-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with care to avoid inhaling the powder. Follow standard safety procedures and consult the Safety Data Sheet (SDS) for further guidance. The compound is stable in dry conditions but should be stored in a cool, dry place away from strong acids and bases.
Related Compounds
![[(3aS,5R,6S,6aS)-6-Hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl](4-morpholinyl)methanone (non-preferred name) structure](https://static.chemtradehub.com/structs/110/1103738-19-7-ae24.webp "[(3aS,5R,6S,6aS)-6-Hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl](4-morpholinyl)methanone (non-preferred name) structure")
[(3aS,5R,6S,6aS)-6-Hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl](4-morpholinyl)methanone (non-preferred name)
CAS Number:
1103738-19-7
Molecular Formula:
C12H19NO6
MYO-INOSITOL HEXAKIS(DIHYDROGEN PHOSPHATE), DODECASODIUM SALT HYDRATE
CAS Number:
123408-98-0
Molecular Formula:
C6H8Na12O25P6
2-Methyl-2-propanyl (3S)-3-cyano-1-pyrrolidinecarboxylate
CAS Number:
132945-78-9
Molecular Formula:
C10H16N2O2
![(5R)-5-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-3,4-dihydroxy-2(5H)-furanone structure](https://static.chemtradehub.com/structs/150/15042-01-0-ee1c.webp "(5R)-5-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-3,4-dihydroxy-2(5H)-furanone structure")
(5R)-5-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-3,4-dihydroxy-2(5H)-furanone
CAS Number:
15042-01-0
Molecular Formula:
C9H12O6
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