(2R)-1,1,1-Trifluoro-2-propanamine hydrochloride (1:1)

Basic Information

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CAS Number

177469-12-4

Molecular Formula

C3H7ClF3N

Molecular Weight

149.54 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

SMILES

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CC(C(F)(F)F)N.Cl

InChI

InChI=1S/C3H6F3N.ClH/c1-2(7)3(4,5)6;/h2H,7H2,1H3;1H/t2-;/m1./s1

InChIKey

VLVCERQEOKPRTG-HSHFZTNMSA-N

LogP

1.3177

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

57.7

Safety Information

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Hazard Statement

Synonyms & References

English

(R)-1,1,1-TRIFLUOROPROPAN-2-AMINE HYDROCHLORIDE
DTXSID90659602
SCHEMBL2253880
BCP14786
(R)-1,1,1-Trifluoroisopropylamine hydrochloride
EN300-216037
(R)-1,1,1-TRIFLUOROPROPAN-2-AMINEHYDROCHLORIDE
(2R)-1,1,1-Trifluoropropan-2-amine--hydrogen chloride (1/1)
DS-13469
AC-25829
2-Propanamine, 1,1,1-trifluoro-, hydrochloride (1:1), (2R)-
AMY3240
AKOS005063313
(R)-1,1,1-trifluoroisopropylamine HCl
(R)-2-Amino-1,1,1-trifluoropropane hydrochloride
(2R)-1,1,1-trifluoropropan-2-amine hydrochloride
(R)-2-AMINO-1,1,1-TRIFLUOROPROPANE HCL
A881464
(R)-1-methyl-2,2,2-trifluoro-ethylamine hydrochloride
(R)-1-methyl-2,2,2-trifluoroethylamine hydrochloride
MFCD07779095
(R)-1,1,1-Trifluoropropan-2-amine HCl
2-Propanamine, 1,1,1-trifluoro-, hydrochloride, (2R)-
CS-W006413
?(S)-1,1,1-TRIFLUOROISOPROPYLAMINE HYDROCHLORIDE
177469-12-4
(2R)-1,1,1-trifluoropropan-2-amine;hydrochloride
FD2033
(R)-1,1,1-Trifluoropropan-2-amine hydrochloride
R-TFIPMHCL
(R)-1,1,1-TRIFLUOROISOPROPYLAMINE HYDROCHLORIDE

MDL Number

MFCD07779095

FAQ

What are the physical and chemical properties of (2R)-1,1,1-Trifluoro-2-propanamine hydrochloride (CAS: 177469-12-4)?

(2R)-1,1,1-Trifluoro-2-propanamine hydrochloride (CAS: 177469-12-4) is a crystalline compound with a molecular weight of approximately 199.6 g/mol. It has a low solubility in water but is soluble in most organic solvents. The compound is moderately reactive, especially under basic conditions. It can form stable complexes with metal ions and is often used in various chemical reactions due to its unique structure.

How is (2R)-1,1,1-Trifluoro-2-propanamine hydrochloride (CAS: 177469-12-4) typically synthesized?

(2R)-1,1,1-Trifluoro-2-propanamine hydrochloride (CAS: 177469-12-4) is typically synthesized by first preparing the amine and then reacting it with trifluoroacetic acid to form the hydrochloride salt. Common methods include direct acidification of the amine with hydrochloric acid or using trifluoroacetic anhydride with the amine. The yield and selectivity are generally good, with purification typically achieved by recrystallization from appropriate solvents.

What industries use (2R)-1,1,1-Trifluoro-2-propanamine hydrochloride (CAS: 177469-12-4)?

(2R)-1,1,1-Trifluoro-2-propanamine hydrochloride (CAS: 177469-12-4) is primarily used in the pharmaceutical industry for its role in synthesizing active pharmaceutical ingredients (APIs). It is also used in the polymer industry for stabilizing polymers and in the semiconductor industry for etching processes. Additionally, it finds applications in the sensor industry for detecting certain chemical species.

What precautions should be taken when handling (2R)-1,1,1-Trifluoro-2-propanamine hydrochloride (CAS: 177469-12-4)?

When handling (2R)-1,1,1-Trifluoro-2-propanamine hydrochloride (CAS: 177469-12-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using absorbent materials and disposing of the waste in accordance with local regulations. Always consult the safety data sheet (SDS) for detailed handling and disposal instructions.