Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate(CAS: 135207-08-8)

Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8) is a colorless to white crystalline solid with a molecular weight of approximately 226.27 g/mol. It has a pKa of around 4.2 and is soluble in organic solvents like ethanol and acetone but less soluble in water. The compound is relatively stable under normal conditions but can react with strong bases. It is used in various chemical reactions and synthetic pathways.

Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8) can be synthesized through a multi-step process that involves the reaction of 2-cyclopropyl-1,3-thiazole with ethyl chloroformate followed by hydrolysis. The reaction is typically carried out under mild conditions and can be catalyzed by a suitable acid or base. The yield can be enhanced by optimizing the reaction conditions and using appropriate solvents.

Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8) is used in the pharmaceutical industry for the synthesis of various organic compounds and in the production of certain medications. It also finds applications in the polymer industry for developing specific plastic materials and in the production of sensors and semiconductors for electronic devices.

When handling Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8), it is important to use personal protective equipment (PPE) such as gloves and safety goggles. The compound should be handled in a fume hood to avoid inhalation. In case of a spill, it should be carefully cleaned up using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.