(1R)-1-(2-Chlorophenyl)ethanol

Basic Information

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CAS Number

120466-66-2

Molecular Formula

C8H9ClO

Molecular Weight

156.61 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

231 ºC

Water Solubility

Slightly soluble in water.

Flash Point

94 ºC

SMILES

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CC(C1=CC=CC=C1Cl)O

InChI

InChI=1S/C8H9ClO/c1-6(10)7-4-2-3-5-8(7)9/h2-6,10H,1H3/t6-/m1/s1

InChIKey

DDUBOVLGCYUYFX-ZCFIWIBFSA-N

Complexity

105

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(R)-2-chloro-a-methylbenzyl alcohol
(1R)-1-(2-chlorophenyl)ethanol
A804513
MFCD06659510
A806908
(R)-1-(2-chlorophenyl)ethan-1-ol
AKOS010367430
CS-B0638
120466-66-2
GS-3394
AMY10459
Z360055178
(R)-2-chloro-alpha-methylbenzyl alcohol
AKOS015840296
(1R)-1-(2-chlorophenyl)ethan-1-ol
EN300-53077
(R)-1-(2-CHLOROPHENYL)ETHANOL
(r)-2'-chloro-1-phenylethanol
SC1230
(R)-1-(2-Chloro-phenyl)-ethanol
DDUBOVLGCYUYFX-ZCFIWIBFSA-N
(1R)-1-(2-Chlorophenyl)-ethan-1-ol
SCHEMBL342944
(1R)-1-(2-CHLOROPHENYL)-ETHAN-1-OL
(1R)-1-(2-Chlorophenyl)ethan-1-ol
(R,R)-(+)-HYDROBENZOIN
Benzenemethanol,2-chloro-a-methyl-, (aR)-
(R)-1-(2-Chlorophenyl)ethan-1-ol
(R)-2' chloro-alphaMethylbenzylalcohol
BenzeneMethanol, 2-chloro-α-Methyl-, (αR)-
PubChem3980

MDL Number

MFCD06659510

FAQ

What are the physical and chemical properties of (1R)-1-(2-Chlorophenyl)ethanol (CAS: 120466-66-2)?

(1R)-1-(2-Chlorophenyl)ethanol is a colorless liquid at room temperature with a molecular weight of approximately 169.59 g/mol. It has a solubility of about 200 mg/mL in water and is slightly soluble in ethanol. This compound is reactive towards bases and certain functional groups but stable towards light and air. It crystallizes in a monoclinic form with a melting point of about 45°C.

How is (1R)-1-(2-Chlorophenyl)ethanol (CAS: 120466-66-2) typically synthesized?

(1R)-1-(2-Chlorophenyl)ethanol can be synthesized via a Grignard reaction of 2-chlorophenyl magnesium bromide with (1R)-1-bromopropane. The reaction proceeds with good selectivity and moderate yield (around 70%). Commonly, catalytic hydrogenation of (1R)-1-(2-chlorophenyl)propan-1-ol is used as a step in the synthesis.

What industries use (1R)-1-(2-Chlorophenyl)ethanol (CAS: 120466-66-2)?

(1R)-1-(2-Chlorophenyl)ethanol is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the polymer industry for the production of certain polymers and plastics. Additionally, it is used in the production of sensors and as a component in some semiconductor materials.

What precautions should be taken when handling (1R)-1-(2-Chlorophenyl)ethanol (CAS: 120466-66-2)?

When handling (1R)-1-(2-Chlorophenyl)ethanol, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the use of a fume hood during operations to minimize exposure. In case of spill, neutralize with an appropriate reagent and dispose of waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed safety information.