6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine | CAS No. 1188993-09-0

6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine

Basic Information

CAS Number

1188993-09-0

Molecular Formula

C22H38N2O2Si2

Molecular Weight

418.73 g/mol

AD

Basic Physical Properties

CC(C)(C)[Si](C)(C)OCC1CCN(C1)CC2=CC3=C(C=C(O3)[Si](C)(C)C)N=C2

InChI

InChI=1S/C22H38N2O2Si2/c1-22(2,3)28(7,8)25-16-17-9-10-24(14-17)15-18-11-20-19(23-13-18)12-21(26-20)27(4,5)6/h11-13,17H,9-10,14-16H2,1-8H3

InChIKey

FYIVFWBKWAFZGA-UHFFFAOYSA-N

LogP

5.216700000000006

Topological Polar Surface Area

38.5 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

530

Safety Information

View Safety Information

GHS Hazard Pictograms

H302H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

  • 6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyrid
  • 6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolid in-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyri
  • tert-butyl-dimethyl-[[1-[(2-trimethylsilylfuro[3,2-b]pyridin-6-yl)methyl]pyrrolidin-3-yl]methoxy]silane
  • A-6136
  • 6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine
  • 1188993-09-0
  • MFCD13176659
  • 6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolid in-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyrid
  • 6-[3-(tert-Butyldimethylsilyloxymethyl)pyrrolidin-1-ylmethyl]-2-(trimethylsilyl)furo[3,2-b]pyridine
  • 6-{[3-({[tert-Butyl(dimethyl)silyl]oxy}methyl)pyrrolidin-1-yl]methyl}-2-(trimethylsilyl)furo[3,2-b]pyridine
  • CS-0442205
  • AKOS025394199
  • 6-((3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine
  • 3-{[(tert-butyldimethylsilyl)oxy]methyl}-1-{[2-(trimethylsilyl)furo[3,2-b]pyridin-6-yl]methyl}pyrrolidine
  • DTXSID10674115
  • 6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine, AldrichCPR

MDL Number

MFCD13176659

FAQ

What are the physical and chemical properties of 6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine (CAS: 1188993-09-0)?

The compound is a crystalline solid with a molecular weight of approximately 625.5 g/mol. It has low solubility in water but is soluble in organic solvents like dichloromethane and acetonitrile. The compound exhibits moderate reactivity, particularly towards nucleophiles and bases. It is stable under normal conditions but should be stored in a dry and cool environment to avoid hydrolysis.

How is 6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine (CAS: 1188993-09-0) typically synthesized?

The compound is typically synthesized via a multistep process involving the formation of a silyl ether from pyrrolidine and tert-butyldimethylsilyl chloride, followed by coupling with furo[3,2-b]pyridine. The synthesis involves sensitive steps that require the use of appropriate solvents and mild conditions to achieve high yield and selectivity. Common solvents include dichloromethane and tetrahydrofuran.

What industries use 6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine (CAS: 1188993-09-0)?

This compound is primarily used in pharmaceuticals and fine chemistry for the synthesis of drug intermediates. Its unique chemical structure makes it valuable in developing new medicinal agents. It may also find applications in polymer chemistry for the modification of polymers and in sensor technology for developing advanced detection systems.

What precautions should be taken when handling 6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine (CAS: 1188993-09-0)?

Proper personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. The compound should be handled in a fume hood due to its potential volatility and reactivity. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

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