Compound Q&A
How is 4'-Fluoro-3'-nitrobiphenyl-3-carboxylic acid (CAS: 1280786-72-2) typically synthesized?
Answer
4'-Fluoro-3'-nitrobiphenyl-3-carboxylic acid (CAS: 1280786-72-2) is typically synthesized via the nitration of 4'-fluorobiphenyl followed by carboxylation. Commonly used reagents include nitric acid and sulfuric acid for nitration, and carboxylation is achieved using carbon dioxide. The yield is generally around 70-80%.
About
CAS No
1280786-72-2
English Name
4'-Fluoro-3'-nitrobiphenyl-3-carboxylic acid
Molecular Formula
C13H8FNO4
Molecular Weight
261.2053 g/mol
SMILES
C1=CC(=CC(=C1)C(=O)O)C2=CC(=C(C=C2)F)[N+](=O)[O-]
InChIKey
TXSMMXNGTYCZST-UHFFFAOYSA-N
Last Updated: 2026-04-02 10:24
