Compound Q&A

How is 1-(4-Pyridinylmethyl)guanidine (CAS: 45957-41-3) typically synthesized?

Answer

1-(4-Pyridinylmethyl)guanidine
1-(4-Pyridinylmethyl)guanidine is typically synthesized via the reaction of 4-pyridinemethylamine with guanidine hydrochloride in the presence of a suitable solvent like DMF. The reaction is catalyzed by a mild base and is known for its good yield and high selectivity. The process involves a nucleophilic substitution followed by an amidation reaction, leading to the formation of the desired product.

About

CAS No 45957-41-3
English Name 1-(4-Pyridinylmethyl)guanidine
Molecular Formula C7H10N4
Molecular Weight 150.19 g/mol
SMILES C1=CN=CC=C1CN=C(N)N
InChIKey GBLIODJTYTUZIW-UHFFFAOYSA-N
Last Updated: 2026-04-01 19:31

Related Q&A

Compound Q&A

What are the physical and chemical properties of 1-(4-Pyridinylmethyl)guanidine (CAS: 45957-41-3)?

1-(4-Pyridinylmethyl)guanidine (CAS: 45957-41-3) is a white crystalline solid with a molecular weigh...

Compound Q&A

What industries use 1-(4-Pyridinylmethyl)guanidine (CAS: 45957-41-3)?

1-(4-Pyridinylmethyl)guanidine (CAS: 45957-41-3) is primarily used in the pharmaceutical industry as...

Compound Q&A

What precautions should be taken when handling 1-(4-Pyridinylmethyl)guanidine (CAS: 45957-41-3)?

When handling 1-(4-Pyridinylmethyl)guanidine (CAS: 45957-41-3), it is essential to wear appropriate ...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...