Compound Q&A

How is (2Z)-2-(2-Amino-1,3-thiazol-4-yl)-1-(1H-benzotriazol-1-yl)-2-(methoxyimino)ethanone (CAS: 71445-20-0) typically synthesized?

Answer

(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-1-(1H-benzotriazol-1-yl)-2-(methoxyimino)ethanone
(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-1-(1H-benzotriazol-1-yl)-2-(methoxyimino)ethanone is typically synthesized by the condensation of 2-amino-1,3-thiazole-4-carboxylic acid with 1H-benzotriazole-1-carboxylic acid anhydride, followed by the formation of the methoxyimino derivative. The reaction is catalyzed by a Lewis acid such as trifluoromethanesulfonic acid, and the yield is generally high, with good selectivity towards the desired product.

About

CAS No 71445-20-0
English Name (2Z)-2-(2-Amino-1,3-thiazol-4-yl)-1-(1H-benzotriazol-1-yl)-2-(methoxyimino)ethanone
Molecular Formula C12H10N6O2S
Molecular Weight 302.32 g/mol
SMILES CON=C(C1=CSC(=N1)N)C(=O)ON2C3=CC=CC=C3N=N2
InChIKey GOMKFKYGVDTXQQ-YBEGLDIGSA-N
Last Updated: 2026-03-31 22:55

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