(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-1-(1H-benzotriazol-1-yl)-2-(methoxyimino)ethanone(CAS: 71445-20-0)

(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-1-(1H-benzotriazol-1-yl)-2-(methoxyimino)ethanone is a crystalline compound with a molecular weight of approximately 354.38 g/mol. It has a slight solubility in water and is insoluble in organic solvents. This compound is known for its reactivity towards nucleophiles and its ability to form strong complexes with metal ions. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-1-(1H-benzotriazol-1-yl)-2-(methoxyimino)ethanone is typically synthesized by the condensation of 2-amino-1,3-thiazole-4-carboxylic acid with 1H-benzotriazole-1-carboxylic acid anhydride, followed by the formation of the methoxyimino derivative. The reaction is catalyzed by a Lewis acid such as trifluoromethanesulfonic acid, and the yield is generally high, with good selectivity towards the desired product.

(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-1-(1H-benzotriazol-1-yl)-2-(methoxyimino)ethanone is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of bioactive compounds. It is also utilized in the development of sensors and in the production of certain polymers due to its unique chemical properties and reactivity.

When handling (2Z)-2-(2-Amino-1,3-thiazol-4-yl)-1-(1H-benzotriazol-1-yl)-2-(methoxyimino)ethanone, ensure to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Spills should be contained and cleaned up using appropriate chemicals, and the area should be thoroughly rinsed. Refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.