Compound Q&A
How is 1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride (CAS: 37148-49-5) typically synthesized?
Answer
![1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride (1:1)](https://static.chemtradehub.com/structs/371/37148-49-5-8d44.webp "1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride (1:1)")
1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride is typically synthesized via a multistep procedure involving the condensation of 4-amino-3,5-dichlorophenylamine with 2-(2-methyl-2-propanyl)ethanone followed by hydrochloric acid treatment. The reaction is performed under mild conditions in the presence of a suitable solvent, such as methanol, with high selectivity and yield.
About
CAS No
37148-49-5
English Name
1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride (1:1)
Molecular Formula
C12H17Cl3N2O
Molecular Weight
311.64 g/mol
SMILES
CC(C)(C)NCC(=O)C1=CC(=C(C(=C1)Cl)N)Cl.Cl
InChIKey
VCMBTLCRANMPCO-UHFFFAOYSA-N
Last Updated: 2026-03-31 22:55
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