1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride (1:1)(CAS: 37148-49-5)

1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride (CAS: 37148-49-5) is a crystalline solid with a molecular weight of approximately 432.95 g/mol. It has a solubility of about 1.2 g/L in water and is slightly soluble in ethanol. The compound is moderately reactive with strong acids and bases. It exhibits good stability under standard storage conditions but should be protected from moisture and light.

1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride is typically synthesized via a multistep procedure involving the condensation of 4-amino-3,5-dichlorophenylamine with 2-(2-methyl-2-propanyl)ethanone followed by hydrochloric acid treatment. The reaction is performed under mild conditions in the presence of a suitable solvent, such as methanol, with high selectivity and yield.

1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride (CAS: 37148-49-5) is primarily used in the pharmaceutical industry, particularly in the synthesis of drug intermediates. It is also used in the production of certain sensors and in some polymer formulations due to its specific chemical properties.

When handling 1-(4-Amino-3,5-dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]ethanone hydrochloride (CAS: 37148-49-5), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly rinsed. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information.