Compound Q&A
How is 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine (CAS: 81794-13-0) typically synthesized?
Answer
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine](https://static.chemtradehub.com/structs/817/81794-13-0-da8f.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine is typically synthesized through multistep reactions involving condensation and silylation processes. The synthesis involves the use of protecting groups and catalysts to ensure high yield and selectivity. Commonly, trifluoroacetic acid (TFA) is used as a catalyst for the deprotection step, while silylation is typically achieved using trimethylchlorosilane (TMCS) and 4-dimethylaminopyridine (DMAP) as reagents.
About
CAS No
81794-13-0
English Name
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine
Molecular Formula
C37H45N5O6Si
Molecular Weight
683.88 g/mol
SMILES
O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O[Si](C)(C(C)(C)C)C)[C@H]3COC(C4=CC=C(OC)C=C4)(C5=CC=CC=C5)C6=CC=C(OC)C=C6
InChIKey
WBXYUFMFVHCXRR-QSYCCZFCSA-N
Last Updated: 2026-03-31 17:51
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