5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine(CAS: 81794-13-0)

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine is a crystalline compound with a molecular weight of approximately 811.45 g/mol. It has low solubility in water but dissolves readily in organic solvents. The compound is relatively stable under normal conditions but can undergo hydrolysis under acidic or basic conditions. It does not have significant reactivity with common organic compounds under normal laboratory conditions.

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine is typically synthesized through multistep reactions involving condensation and silylation processes. The synthesis involves the use of protecting groups and catalysts to ensure high yield and selectivity. Commonly, trifluoroacetic acid (TFA) is used as a catalyst for the deprotection step, while silylation is typically achieved using trimethylchlorosilane (TMCS) and 4-dimethylaminopyridine (DMAP) as reagents.

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine is primarily used in the pharmaceutical industry for the development of targeted drug delivery systems and in research for understanding the structure-activity relationships of nucleosides. It is also used in the polymer industry for the synthesis of functional polymers and in semiconductor technology for the creation of novel materials with specific properties.

When handling 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine, it is essential to use appropriate personal protective equipment (PPE), including gloves and goggles. The compound should be stored in a cool, dry place away from direct sunlight and should be handled in a fume hood to minimize inhalation risk. In case of spills, they should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. For detailed safety information, refer to the Safety Data Sheet (SDS).