Compound Q&A
How is Methyl 5-bromo-3-[(trifluoroacetyl)amino]-2-thiophenecarboxylate (CAS: 852330-31-5) typically synthesized?
Answer
![Methyl 5-bromo-3-[(trifluoroacetyl)amino]-2-thiophenecarboxylate](https://static.chemtradehub.com/structs/852/852330-31-5-7ae1.webp "Methyl 5-bromo-3-[(trifluoroacetyl)amino]-2-thiophenecarboxylate")
Methyl 5-bromo-3-[(trifluoroacetyl)amino]-2-thiophenecarboxylate (CAS: 852330-31-5) can be synthesized via the reaction of 2-bromo-3-aminothiophene with trifluoroacetic anhydride. The synthesis typically involves the formation of a trifluoroacetyl intermediate, followed by its coupling with the bromo-thiophene derivative. This method provides good yield and selectivity.
About
CAS No
852330-31-5
English Name
Methyl 5-bromo-3-[(trifluoroacetyl)amino]-2-thiophenecarboxylate
Molecular Formula
C8H5BrF3NO3S
Molecular Weight
332.1 g/mol
SMILES
COC(=O)C1=C(C=C(S1)Br)NC(=O)C(F)(F)F
InChIKey
AUIUYLZMPYTXPA-UHFFFAOYSA-N
Last Updated: 2026-03-29 08:05
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