Compound Q&A
How is R-Acalabrutinib (CAS: 1952316-43-6) typically synthesized?
Answer
R-Acalabrutinib is synthesized via a multi-step process involving the protection of a key functional group, followed by a nucleophilic substitution reaction. The synthesis often utilizes palladium catalysts and achieves a high yield. The reaction conditions are carefully optimized to ensure selectivity towards the desired product.
About
CAS No
1952316-43-6
English Name
R-Acalabrutinib
Molecular Formula
C26H23N7O2
Molecular Weight
465.51 g/mol
SMILES
CC#CC(=O)N1CCC[C@@H]1c1nc(c2n1ccnc2N)c1ccc(cc1)C(=O)Nc1ccccn1
InChIKey
OTMSDBZUPAUEDD-UHFFFAOYSA-N
Last Updated: 2026-03-28 19:11
