Compound Q&A
How is Carboxyphosphamide-d4 (CAS: 1246817-74-2) typically synthesized?
Answer
Carboxyphosphamide-d4 (CAS: 1246817-74-2) is synthesized through a multi-step process involving the protection of a carboxyl group, followed by the introduction of a phosphoramidite moiety. The reaction typically requires a coupling agent such as HATU or EDC, and is catalyzed by a base like DIPEA. The process yields a high purity product, with the d4 isotopic label added at the phosphorus atom for enhanced NMR spectroscopy studies.
About
CAS No
1246817-74-2
English Name
Carboxyphosphamide-d4
Molecular Formula
C7H11Cl2D4N2O4P
Molecular Weight
297.1094 g/mol
SMILES
OC(=O)CCOP(=O)(N(CC(Cl)([2H])[2H])CC(Cl)([2H])[2H])N
InChIKey
QLAKAJLYYGOZQL-RRVWJQJTSA-N
Last Updated: 2026-03-28 19:11
