Compound Q&A
How is Methyl 3-benzamidothiophene-2-carboxylate (CAS: 79128-70-4) typically synthesized?
Answer
Methyl 3-benzamidothiophene-2-carboxylate (CAS: 79128-70-4) is typically synthesized via a condensation reaction between methyl thiophene-2-carboxylate and benzamide. The reaction is catalyzed by a Lewis acid such as AlCl3, and the product is isolated by recrystallization from hot ethanol. The yield of the reaction is generally around 85-90%, with high selectivity for the desired product.
About
CAS No
79128-70-4
English Name
Methyl 3-benzamidothiophene-2-carboxylate
Molecular Formula
C13H11NO3S
Molecular Weight
261.302 g/mol
SMILES
COC(=O)C1=C(C=CS1)NC(=O)C2=CC=CC=C2
InChIKey
ILRZDTPFHHAMMM-UHFFFAOYSA-N
Last Updated: 2026-03-28 19:11
